Immunogen sequence: KGKLLSSQEG MISFDCFMTI LMQMRRSLGS SADRSQWREP TRTSDGLCSL YEAALCLFEE VCRMASDYSR TCASPDSIQT GDAPIVSETC EVYVWGSNSS HQLVEGTQEK ILQPK
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: guanine nucleotide exchange factor p532; hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1; HECT domain and RCC1-like domain-containing protein 1; HECT-type E3 ubiquitin transferase HERC1; p532; p619; Probable E3 ubiquitin-protein ligase HERC1
Gene Aliases: HERC1; p532; p619
UniProt ID: (Human) Q15751
Entrez Gene ID: (Human) 8925
Molecular Function: guanyl-nucleotide exchange factor