|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 400-429 amino acids from the central region of human HERV (ERVWE1)|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: endogenous retroviral family W, env(C7), member 1; Endogenous retrovirus group W member 1; endogenous retrovirus group W, member 1; Env-W; envelope glycoprotein; Envelope polyprotein gPr73; Enverin; ERVWE1; HERV-7q Envelope protein; HERV-tryptophan envelope protein; HERV-W Env glycoprotein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; human endogenous retrovirus W envC7-1 envelope protein; Surface protein; Syncytin; syncytin A; Syncytin-1; Transmembrane protein
Gene Aliases: ENV; ENVW; ERVW-1; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV
UniProt ID: (Human) Q9UQF0
Entrez Gene ID: (Human) 30816
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