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Product Details
PA5-22819
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues 42-50 of the HERV protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152722
Target Information
HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: endogenous retroviral family W, env(C7), member 1; Endogenous retrovirus group W member 1; endogenous retrovirus group W, member 1; Env-W; envelope glycoprotein; Envelope polyprotein gPr73; envelope protein; Enverin; HERV-7q Envelope protein; HERV-tryptophan envelope protein; HERV-W Env glycoprotein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; human endogenous retrovirus W envC7-1 envelope protein; Syncytin; syncytin A; Syncytin-1
Gene Aliases: ENV; ENVW; ERVW-1; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV
UniProt ID: (Human) Q9UQF0
Entrez Gene ID: (Human) 30816
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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