This antibody is predicted to react with bovine, mouse, rat and Xenopus based on sequence homology.
HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES1 has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHb39; Class B basic helix-loop-helix protein 39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like; Hairy-like protein; HHL; HRY; Transcription factor HES-1
Gene Aliases: BHLHB39; HES-1; HES1; HHL; HL; HRY
UniProt ID: (Human) Q14469
Entrez Gene ID: (Human) 3280