PA5-28802 targets HES1 in WB applications and shows reactivity with Human samples.
The PA5-28802 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human HES1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
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Protein Aliases: bHLHb39; Class B basic helix-loop-helix protein 39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; HES-1; HHL; HRY; Transcription factor HES-1
Gene Aliases: BHLHB39; HES-1; HES1; HHL; HL; HRY
UniProt ID: (Human) Q14469
Entrez Gene ID: (Human) 3280