Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse kidney, PC-12.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHb39; Class B basic helix-loop-helix protein 39; FLJ20408; Hairy and enhancer of split 1; Hairy homolog; Hairy-like; Hairy-like protein; hHL; RHL; Transcription factor HES-1
Gene Aliases: BHLHB39; HES-1; HES1; HHL; HL; HRY
Molecular Function: basic helix-loop-helix transcription factor