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Proteintech
HESX1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
17927-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HESX1 Fusion Protein Ag12348 (1-185 aa encoded by BC093979)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSPSLQEGA QLGENKPSTC SFSIERILGL DQKKDCVPLM KPHRPWADTC SSSGKDGNLC LHVPNPPSGI SFPSVVDHPM PEERASKYEN YFSASERLSL KRELSWYRGR RPRTAFTQNQ IEVLENVFRV NCYPGIDIRE DLAQKLNLEE DRIQIWFQNR RAKLKRSHRE SQFLMAKKNF NTNLLE (1-185 aa encoded by B C093979)
Target Information
This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1-related growth hormone deficiency, and combined pituitary hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anterior-restricted homeobox protein; Hesx1; homeo box gene expressed in ES cells; homeobox protein ANF; rathke pouch homeo box; Rathke pouch homeobox; Rathke's pouch homeobox; unnamed protein product
Gene Aliases: ANF; CPHD5; HES-1; RGD1563858; RPX
UniProt ID: (Human) Q9UBX0, (Mouse) Q61658
Entrez Gene ID: (Human) 8820, (Rat) 498575, (Mouse) 15209
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
protein binding
protein homodimerization activity
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
brain development
biological_process
gonad development
gene expression
Wnt signaling pathway
stem cell population maintenance
pituitary gland development
thyroid gland development
forebrain development
otic vesicle formation
multicellular organism growth
camera-type eye development
nose development
negative regulation of transcription, DNA-templated
regulation of embryonic development
forebrain morphogenesis
leukemia inhibitory factor signaling pathway
stem cell differentiation
canonical Wnt signaling pathway
ERK1 and ERK2 cascade
cellular response to cadmium ion
ectoderm development
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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