15676-1-AP recognizes both 70 and 54 kDa bands.
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
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Protein Aliases: Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; FLJ13562; hexamethylene bis-acetamide inducible 1; Hexamethylene bis-acetamide-inducible protein 1; hexamethylene bisacetamide-inducible protein; hexamethylene-bis-acetamide-inducible transcript 1; hexamthylene bis-acetamide inducible 1; HGNC:24953; HMBA-inducible; menage a quatre 1; Menage a quatre protein 1; Protein HEXIM1
Gene Aliases: 7330426E13Rik; CLP-1; CLP1; EDG1; HEXIM1; HIS1; MAQ1