PA5-31076 targets HEY1 in WB applications and shows reactivity with Human samples.
The PA5-31076 immunogen is recombinant fragment corresponding to a region within amino acids 12 and 304 of Human HEY1.
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This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
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Protein Aliases: basic helix-loop-helix protein OAF1; BHLHb31; Cardiovascular helix-loop-helix factor 2; CHF-2; CHF2; Class B basic helix-loop-helix protein 31; Hairy and enhancer of split-related protein 1; hairy-related transc; Hairy-related transcription factor 1; hairy/enhancer-of-split related with YRPW motif 1; Hairy/enhancer-of-split related with YRPW motif protein 1; HERP2; hes-related family bHLH transcription factor with YRPW motif 1; HES-related repressor protein 1; HES-related repressor protein 2; HESR-1; HESR1; hHRT1; HRT-1; OAF1
Gene Aliases: BHLHB31; CHF2; HERP2; HESR1; HEY1; hHRT1; HRT-1; HRT1; OAF1
UniProt ID: (Human) Q9Y5J3
Entrez Gene ID: (Human) 23462