Search

  • Order Status
  • 快速訂購

Bioss

HEY2 Polyclonal Antibody

View all (9) HEY2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

Product Details

BS-9461R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human HEY2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: bHLHb32; cardiovascular basic helix-loop-helix factor 1; Cardiovascular helix-loop-helix factor 1; CHF1; Class B basic helix-loop-helix protein 32; h hHRT2; hairy and enhancer of split related 2; Hairy and enhancer of split-related protein 2; Hairy-E(spl)-related with YRPW motif 2; Hairy-related transcription factor 2; hairy/enhancer-of-split related with YRPW motif 2; Hairy/enhancer-of-split related with YRPW motif protein 2; hCHF1; HES-related repressor protein 1; HES-related repressor protein 2; HESR-2; hGRL; basic helix-loop-helix transcription factor; hHRT2; HRT-2; HRT2; mHRT2; Protein gridlock homolog; transcription factor; unnamed protein product

View more View less

Gene Aliases: BHLHB32; CHF1; GRIDLOCK; GRL; HERP; HERP1; HESR2; HEY2; HRT2

View more View less

UniProt ID: (Human) Q9UBP5, (Mouse) Q9QUS4

View more View less

Entrez Gene ID: (Human) 23493, (Mouse) 15214, (Rat) 155430

View more View less

Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding identical protein binding histone deacetylase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II sequence-specific DNA binding transcription factor binding sequence-specific double-stranded DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, protein binding RNA polymerase II activating transcription factor binding transcription factor binding microsatellite binding molecular_function basic helix-loop-helix transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter blood vessel development vasculogenesis muscular septum morphogenesis outflow tract morphogenesis cardiac conduction system development atrioventricular valve development aortic valve morphogenesis pulmonary valve morphogenesis tricuspid valve morphogenesis tricuspid valve formation epithelial to mesenchymal transition involved in endocardial cushion formation endocardial cushion to mesenchymal transition involved in heart valve formation cardiac ventricle morphogenesis cardiac left ventricle morphogenesis cardiac right ventricle morphogenesis ventricular trabecula myocardium morphogenesis cardiac muscle hypertrophy regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter Notch signaling pathway pattern specification process heart development anatomical structure morphogenesis anterior/posterior axis specification anterior/posterior pattern specification positive regulation of heart rate regulation of gene expression negative regulation of gene expression cardiac muscle cell apoptotic process negative regulation of cardiac muscle cell apoptotic process mesenchymal cell development cardiac muscle hypertrophy in response to stress ascending aorta morphogenesis dorsal aorta morphogenesis umbilical cord morphogenesis cell fate commitment regulation of auditory receptor cell differentiation negative regulation of Notch signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of neurogenesis smooth muscle cell differentiation negative regulation of smooth muscle cell differentiation ventricular cardiac muscle cell development cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition heart trabecula formation cardiac septum morphogenesis ventricular septum morphogenesis atrial septum morphogenesis negative regulation of transcription initiation from RNA polymerase II promoter labyrinthine layer blood vessel development blood vessel endothelial cell differentiation artery development arterial endothelial cell differentiation cardiac vascular smooth muscle cell development coronary vasculature morphogenesis pulmonary artery morphogenesis protein-DNA complex assembly negative regulation of biomineral tissue development circulatory system development cochlea development vascular smooth muscle cell development negative regulation of cardiac vascular smooth muscle cell differentiation regulation of vasculogenesis transcription, DNA-templated transcription from RNA polymerase II promoter multicellular organism development Notch signaling involved in heart development negative regulation of transcription regulatory region DNA binding negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support