Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: basic helix-loop-helix transcription factor; gridlock; h hHRT2; hairy/enhancer-of-split related with YRPW motif 2; Hairy/enhancer-of-split related with YRPW motif protein 2; Herp2; Protein gridlock
Gene Aliases: grl; hey2; zgc:136746
UniProt ID: (Zebrafish) Q9I9L0
Entrez Gene ID: (Zebrafish) 58146