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Invitrogen
HHATL Polyclonal Antibody
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Product Details
PA5-53748
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HHATL. Recombinant protein control fragment (Product #RP-90837).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ASFKMDPLIS WQSGFVTGTF DLQEVLFHGG SSFTVLRCTS FALESCAHPD RHYSLADLLK YNFYLPFFFF GPIMTFDRFH AQVSQVEPVR REGELWHIRA Q
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 90%.
Target Information
HHATL (Hedgehog Acyltransferase-Like) is a gene that codes for a protein involved in the regulation of Hedgehog signaling pathways. HHATL is located on chromosome 7q36.3. Structurally, the protein encoded by this gene is characterized by an acyltransferase domain, which plays a crucial role in the N-palmitoylation of the Sonic Hedgehog (Shh) protein, a process essential for its proper signaling activity and distribution. Functionally, HHATL has been implicated in various biological processes, including amelioration of endoplasmic reticulum stress through autophagy. The gene is expressed in several tissues, with notable high expression in the heart, suggesting a potential role in cardiac development and function. Dysfunction in HHATL could lead to anomalies in Hedgehog signaling, impacting various developmental and cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycerol uptake/transporter homolog; GUP1 glycerol uptake/transporter homolog; Hedgehog acyltransferase-like protein; membrane bound O-acyltransferase domain containing 3; Protein-cysteine N-palmitoyltransferase HHAT-like protein
Gene Aliases: C3orf3; GUP1; HHATL; KIAA1173; MBOAT3; MSTP002; OACT3
UniProt ID: (Human) Q9HCP6
Entrez Gene ID: (Human) 57467
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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