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Abnova
HIF3A Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
HIF3A Antibody (H00064344-B01P) in WB
Western Blot analysis of HIF3A expression in transfected 293T cell line (H00064344-T01) by HIF3A MaxPab polyclonal antibody.
Lane 1: HIF3A transfected lysate(40.04 KDa).
Lane 2: Non-transfected lysate.
Lane 1: HIF3A transfected lysate(40.04 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00064344-B01P
Product Specifications
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HIF3A (AAH26308, 1 a.a. approximately 363 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MALGLQRARS TTELRKEKSR DAARSRRSQE TEVLYQLAHT LPFARGVSAH LDKASIMRLT ISYLRMHRLC AAGEWNQVGA GGEPLDACYL KALEGFVMVL TAEGDMAYLS ENVSKHLGLS QLELIGHSIF DFIHPCDQEE LQDALTPQQT LSRRKVEART ERCFSLRMKS TLTSRGRTLN LKAATWKVLN CSGHMRAYKP PAQTSPAGSP DSEPPLQCLV LICEAIPHPG SLEPPLGRGA FLSRHSLDMK FTYCDDRIAE VAGYSPDDLI GCSAYEYIHA LDSDAVSKSI HTCMYPISPG AKPAATWPPA DTRTPQLPIP QDALPPHLNT SSLLPKPQGT VSFLAPSYPV PRSFSPHLPP WWP
Target Information
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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