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Abnova
HINT1 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
HINT1 Antibody (H00003094-B01P) in WB
Western Blot analysis of HINT1 expression in transfected 293T cell line (H00003094-T02) by HINT1 MaxPab polyclonal antibody.
Lane 1: HINT1 transfected lysate(13.86 KDa).
Lane 2: Non-transfected lysate.
Lane 1: HINT1 transfected lysate(13.86 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00003094-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HINT1 (NP_005331.1, 1 a.a. approximately 126 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MADEIAKAQV ARPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI SQISVAEDDD ESLLGHLMIV GKKCAADLGL NKGYRMVVNE GSDGGQSVYH VHLHVLGGRQ MHWPPG
Target Information
Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenosine 5'-monophosphoramidase; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; FLJ30414; FLJ32340; Histidine triad nucleotide-binding protein 1; PKCI-1; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1
Gene Aliases: HINT; HINT1; NMAN; PKCI-1; PKCI1; PRKCNH1
UniProt ID: (Human) P49773
Entrez Gene ID: (Human) 3094
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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