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Invitrogen
HK1 Monoclonal Antibody (R.457.3)
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Product Details
MA5-14789
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
C. elegans,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
R.457.3
Immunogen
Synthetic peptide corresponding to the sequence of human hexokinase I
Conjugate
Form
Liquid
Concentration
127 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase I; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I
Gene Aliases: BB404130; dea; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s
UniProt ID: (Human) E9PCK0, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Mouse) 15275
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
mannokinase activity
nucleotide binding
catalytic activity
protein kinase activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
protein complex binding
protein homodimerization activity
kinase
cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
response to ischemia
carbohydrate metabolic process
protein phosphorylation
metabolic process
regulation of anion channel activity
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
negative regulation of apoptotic process
protein autophosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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