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NeoBiotechnologies
HLA-DP (MHC II) Recombinant Rabbit Monoclonal Antibody (HLA-DPB1/2862R)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
3115-RBM4-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HLA-DPB1/2862R
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and -DP, all are highly polymorphic. HLA-DP molecules have not been studied extensively. HLA-DP is a protein complex found on the surface of antigen-presenting cells, such as dendritic cells, macrophages, and B cells. Its main function is to present peptides derived from extracellular proteins to CD4+ T cells for immune recognition.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DP beta 1 domain protein; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA DP4 beta-chain; HLA-DP histocompatibility type, beta-1 subunit; light chain; MHC class II antigen DPB1; MHC class II HLA-DP-beta-1; MHC HLA DPB1; MHC HLA-DPw4b-beta chain precursor; MHC HLA-SB-beta chain I; SB-beta chain; unnamed protein product
Gene Aliases: DPB1; HLA-DP; HLA-DP1B; HLA-DPB
UniProt ID: (Human) P04440
Entrez Gene ID: (Human) 3115
peptide antigen assembly with MHC class II protein complex
immune response
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of interferon-gamma production
positive regulation of T cell proliferation
positive regulation of immune response
T cell receptor signaling pathway
positive regulation of T cell activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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