Keep as concentrated solution.
Positive Control: Raji, NCI-H929.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha chain G antibody; b2 microglobulin; b2 microglobulin antibody; class I; G antibody; HLA class I histocompatibility antigen; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA class I molecule antibody; HLA G antigen; HLA G antigen antibody; HLA-G antibody; HLA-G histocompatibility antigen; HLA-G histocompatibility antigen, class I, G; major histocompatibility complex; MHC class I antigen G; MHC class I antigen G antibody; MHC-G antibody; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G
Gene Aliases: HLA-6.0; HLA-G; HLAG; MHC-G
UniProt ID: (Human) P17693
Entrez Gene ID: (Human) 3135