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Homeobox protein HB9 is expressed in lymphoid and pancreatic tissues. It is reported to be Putative transcription factor involved in pancreas development and function. Defects in this gene causes Currarino syndrome. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. It is also reported that HB9 is strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin.
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Protein Aliases: homeobox HB9; Homeobox protein HB9; HOX SCRA1; Motor neuron and pancreas homeobox protein 1
Gene Aliases: HB9; HLXB9; HOXHB9; MNX1; SCRA1
UniProt ID: (Human) P50219
Entrez Gene ID: (Human) 3110