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Proteintech
HMGCL Polyclonal Antibody
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Product Details
16898-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HMGCL Fusion Protein Ag10426 (1-325 aa encoded by BC010570)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAMRKALP RRLVGLASLR AVSTSSMGTL PKRVKIVEVG PRDGLQNEKN IVSTPVKIKL IDMLSEAGLS VIETTSFVSP KWVPQMGDHT EVLKGIQKFP GINYPVLTPN LKGFEAAVAA GAKEVVIFGA ASELFTKKNI NCSIEESFQR FDAILKAAQS ANISVRGYVS CALGCPYEGK ISPAKVAEVT KKFYSMGCYE ISLGDTIGVG TPGIMKDMLS AVMQEVPLAA LAVHCHDTYG QALANTLMAL QMGVSVVDSS VAGLGGCPYA QGASGNLATE DLVYMLEGLG IHTGVNLQKL LEAGNFICQA LNRKTSSKVA QATCKL (1-325 aa encoded by B C010570)
Target Information
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; HL; HMG-CoA lyase; HMGCL; hydroxymethylglutaricaciduria; Hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase; unnamed protein product
Gene Aliases: AW476067; HL; HMGCL; HMGCL1
UniProt ID: (Human) P35914, (Mouse) P38060, (Rat) P97519
Entrez Gene ID: (Human) 3155, (Mouse) 15356, (Rat) 79238
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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