This target displays homology in the following species: Cow: 91%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Yeast: 90%; Zebrafish: 75%
Hmx3 is a transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. This protein binds to the 5'-CAAGTG-3' core sequence. It controls semicircular canal formation in the inner ear and is also required for hypothalamic/pituitary axis of the CNS.
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Protein Aliases: H6 family homeobox 3; H6 homeo box 3; homeo box (H6 family) 3; homeobox (H6 family) 3; Homeobox protein H6 family member 3; Homeobox protein HMX3; Homeobox protein Nkx-5.1; transcription factor
Gene Aliases: HMX3; NKX-5.1; NKX5-1; NKX5.1; RGD1559927; zgc:109845