This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.
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Protein Aliases: A VESL-2; Cupidin; Homer protein homolog 2; homer, neuronal immediate early gene, 2; Homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2
Gene Aliases: 9330120H11Rik; AW539445; CPD; Homer2; Vesl-2; Vesl2
UniProt ID: (Mouse) Q9QWW1
Entrez Gene ID: (Mouse) 26557
Molecular Function: signaling molecule