Peptide sequence: YLTRRRRIEI ANALCLTERQ IKIWFQNRRM KWKKENKLIN STQPSGEDSE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
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Protein Aliases: homeo box 1B; homeo box A6; Homeobox protein Hox-1.2; Homeobox protein Hox-1B; Homeobox protein Hox-A6; homeobox protein HOXA6; Homeobox protein M5-4
Gene Aliases: Hox-1.2; HOX1; HOX1.2; HOX1B; Hoxa-6; HOXA6