Immunogen sequence: VNALFSKYTAG TSLFQNAEPT SCSFAPNSQR SGYGA
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 94%.
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.
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Protein Aliases: homeo box A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A; Homeobox protein Hox-A7
Gene Aliases: ANTP; HOX1; HOX1.1; HOX1A; HOXA7
UniProt ID: (Human) P31268
Entrez Gene ID: (Human) 3204
Molecular Function: homeodomain transcription factor