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This antibody detects endogenous protein at a molecular weight of 30 kDa.
Purity is >95% by SDS-PAGE.
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeo box 2A; homeo box B5; Homeobox protein H24.1; Homeobox protein HHO.C10; Homeobox protein Hox-2.1; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein Hu-1; Homeobox protein Mu-1
Gene Aliases: AI385717; HHO.C10; Hox-2.1; HOX2; Hox2.1; HOX2A; Hoxb-5; HOXB5; HU-1; RGD1562292
UniProt ID: (Human) P09067, (Mouse) P09079
Entrez Gene ID: (Human) 3215, (Rat) 497987, (Mouse) 15413
Molecular Function: homeodomain transcription factor helix-turn-helix transcription factor DNA-binding transcription factor gene-specific transcriptional regulator
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