Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Sequence of this protein is as follows: MSSYLEYVSC SSSGGVGGDV LSLAPKFCRS DARPVALQPA FPLGNGDGAF VSCLPLAAAR PSPSPPAAPA RPSVPPPAAP QYAQCTLEGA YEPGAAPAAA AGGADYGFLG SGPAYDFPGV LGRAADDGGS HVHYATSAVF SGGGSFLLSG QVDYAAFGEP GPFSACLKAS ADGHPGAFQT ASPAPGTYPK SVSPASGLPA AFSTFEWMKV KRNASKKGKL AEYGAASPSS AIRTNFSTKQ LTELEKEFHF NKYLTRARRI EIANCLHLND TQVKIWFQNR RMKQKKRERE GLLATAIPVA PLQLPLSGTT PTKFIKNPGS PSQSQEPS
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
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Protein Aliases: BSAS; homeo box 4G; homeo box A1; homeo box D1; homeobox 1F; homeobox A1; Homeobox protein Hox-D1; Homeobox protein Hox-GG; HOX1; HOX1F; HOX2I; HOXA1; MGC45232
Gene Aliases: Hox-4.7; HOX4; HOX4G; HOXD1
UniProt ID: (Human) Q9GZZ0
Entrez Gene ID: (Human) 3231, (Rat) 288151
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