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Proteintech
HOXD13 Polyclonal Antibody
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Product Details
23520-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HOXD13 Fusion Protein Ag20093 (1-273 aa encoded by BC148863)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSRAGSWDM DGLRADGGGA GGAPASSSSS SVAAAAASGQ CRGFLSAPVF AGTHSGRAAA AAAAAAAAAA AASGFAYPGT SERTGSSSSS SSSAVVAARP EAPPAKECPA PTPAAAAAAP PSAPALGYGY HFGNGYYSCR MSHGVGLQQN ALKSSPHASL GGFPVEKYMD VSGLASSSVP ANEVPARAKE VSFYQGYTSP YQHVPGYIDM VSTFGSGEPR HEAYISMEGY QSWTLANGWN SQVYCTKDQP QGSHFWKSSF PGDVALNQPD MCVY (1-273 aa encoded by BC148863)
Target Information
HOXD13 (homeobox protein D13) belongs to a class of transcription factors called homeobox proteins. In vertebrates, homeobox are found in clusters called A, B, C, and D on four separate chromosomes. Expression of homeobox proteins is spatially and temporally regulated during embryonic development. The gene encoding HOXD13 is part of the D cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in the HOXD13 gene cause synpolydactyly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 4I; homeo box D13; Homeobox protein Hox-4I; Homeobox protein Hox-D13; synpolydactyly
Gene Aliases: BDE; BDSD; HOX4I; HOXD13; SPD; SPD1
UniProt ID: (Human) P35453
Entrez Gene ID: (Human) 3239
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
sequence-specific double-stranded DNA binding
skeletal system development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
pattern specification process
anterior/posterior pattern specification
gland morphogenesis
embryonic limb morphogenesis
male genitalia development
prostate gland development
response to testosterone
limb morphogenesis
regulation of cell proliferation
embryonic digit morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic hindgut morphogenesis
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
morphogenesis of an epithelial fold
branch elongation of an epithelium
regulation of branching involved in prostate gland morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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