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Product Details
BS-8603R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HOXD9, amino acids 251-352.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
HOXD9 is the sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box D9; homeobox Hox-D9; Homeobox protein Hox-4.4; Homeobox protein Hox-4C; Homeobox protein Hox-5.2; Homeobox protein Hox-D9; Hox-4.3, mouse, homolog of
Gene Aliases: Hox-4.3; Hox-4.4; Hox-5.2; HOX4; HOX4C; Hoxd-9; HOXD9
UniProt ID: (Human) P28356, (Mouse) P28357, (Rat) B5DFK3
Entrez Gene ID: (Human) 3235, (Mouse) 15438, (Rat) 688999
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
single fertilization
skeletal muscle tissue development
adult locomotory behavior
anterior/posterior pattern specification
proximal/distal pattern formation
regulation of gene expression
mammary gland development
embryonic forelimb morphogenesis
forelimb morphogenesis
hindlimb morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
embryonic skeletal system development
peripheral nervous system neuron development
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