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Proteintech
HPRT1 Polyclonal Antibody
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Product Details
15059-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HPRT1 Fusion Protein Ag7044 (1-218 aa encoded by BC000578)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATRSPGVV ISDDEPGYDL DLFCIPNHYA EDLERVFIPH GLIMDRTERL ARDVMKEMGG HHIVALCVLK GGYKFFADLL DYIKALNRNS DRSIPMTVDF IRLKSYCNDQ STGDIKVIGG DDLSTLTGKN VLIVEDIIDT GKTMQTLLSL VRQYNPKMVK VASLLVKRTP RSVGYKPDFV GFEIPDKFVV GYALDYNEYF RDLNHVCVIS ETGKAKYKA (1-218 aa encoded by BC000578 )
Target Information
The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HGPRT; HGPRTase; HPRT 1; HPRT B; HPRT1; hypoxanthine guanine phosphoribosyl transferase; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine phosphoribosyl transferase; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89; unnamed protein product
Gene Aliases: C81579; HGPRT; Hgprtase; HPGRT; HPRT; HPRT1
UniProt ID: (Human) P00492, (Mouse) P00493, (Rat) P27605
Entrez Gene ID: (Human) 3251, (Mouse) 15452, (Rat) 24465
nucleotide binding
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity
protein binding
transferase activity
transferase activity, transferring glycosyl groups
identical protein binding
metal ion binding
guanine phosphoribosyltransferase activity
protein homodimerization activity
glycosyltransferase
T cell mediated cytotoxicity
response to amphetamine
purine nucleotide biosynthetic process
purine ribonucleoside salvage
guanine salvage
grooming behavior
locomotory behavior
striatum development
cerebral cortex neuron differentiation
central nervous system neuron development
GMP salvage
IMP salvage
dopamine metabolic process
hypoxanthine salvage
AMP salvage
positive regulation of dopamine metabolic process
GMP catabolic process
IMP metabolic process
adenine metabolic process
hypoxanthine metabolic process
lymphocyte proliferation
dendrite morphogenesis
protein homotetramerization
dopaminergic neuron differentiation
adenine salvage
nucleoside metabolic process
cytolysis
spermatogenesis
brain development
cellular response to insulin stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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