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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HPRT1 Antibodies

          Invitrogen

          HPRT1 Polyclonal Antibody

          View all (31) HPRT1 antibodies

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          Cite HPRT1 Polyclonal Antibody

          • Antibody Testing Data (3)
          HPRT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          HPRT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          HPRT1 Antibody (PA5-25909) in IHC (P)

          Immunohistochemistry analysis of HPRT1 in formalin fixed and paraffin embedded human liver tissue. Samples were incubated with HPRT1 polyclonal antibody (Product # PA5-25909) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HPRT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HPRT1 Antibody in Western Blot (WB)
          HPRT1 Antibody in Flow Cytometry (Flow)
          HPRT1 Polyclonal Antibody

          Product Details

          PA5-25909

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:10-1:50
          -

          Flow Cytometry (Flow)

          1:10-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human HPRT1
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          2 mg/mL

          Purification

          Ammonium sulfate precipitation, Size-exclusion - Dialysis

          Storage buffer

          PBS, pH 7.4

          Contains

          0.09% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2543409

          Product Specific Information

          This antibody is predicted to react with hamster, mouse, porcine, non-human primate and rat based on sequence homology.

          Target Information

          The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: HGPRT; HGPRTase; HPRT 1; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89

          View more View less

          Gene Aliases: HGPRT; HPRT; HPRT1

          View more View less

          UniProt ID: (Human) P00492

          View more View less

          Entrez Gene ID: (Human) 3251

          View more View less

          Function(s)
          nucleotide binding magnesium ion binding hypoxanthine phosphoribosyltransferase activity protein binding protein homodimerization activity guanine phosphoribosyltransferase activity glycosyltransferase
          Process(es)
          response to amphetamine purine nucleotide biosynthetic process purine ribonucleoside salvage adenine salvage guanine salvage grooming behavior locomotory behavior cytolysis striatum development cerebral cortex neuron differentiation central nervous system neuron development GMP salvage IMP salvage dopamine metabolic process purine-containing compound salvage hypoxanthine salvage positive regulation of dopamine metabolic process GMP catabolic process IMP metabolic process hypoxanthine metabolic process lymphocyte proliferation dendrite morphogenesis protein homotetramerization
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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