Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
HRC Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
18142-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HRC Fusion Protein Ag12794 (26-350 aa encoded by BC069795)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTQQLRGDG LGFRNRNNST GVAGLSEEAS AELRHHLHSP RDHPDENKDV STENGHHFWS HPDREKEDED VSKEYGHLLP GHRSQDHKVG DEGVSGEEVF AEHGGQARGH RGHGSEDTED SAEHRHHLPS HRSHSHQDED EDEVVSSEHH HHILRHGHRG HDGEDDEGEE EEEEEEEEEE ASTEYGHQAH RHRGHGSEED EDVSDGHHHH GPSHRHQGHE EDDDDDDDDD DDDDDDDVSI EYRHQAHRHQ GHGIEEDEDV SDGHHHRDPS HRHRSHEEDD NDDDDVSTEY GHQAHRHQDH RKEEVEAVSG EHHHHVPDHR HQGHRD (26-350 aa encoded by BC069795)
Target Information
May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sarcoplasmic reticulum histidine-rich calcium-binding protein
Gene Aliases: HCP; HRC
UniProt ID: (Human) P23327
Entrez Gene ID: (Human) 3270, (Mouse) 15464
regulation of heart rate
muscle contraction
positive regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
regulation of peptidyl-serine phosphorylation
positive regulation of heart contraction
regulation of cytosolic calcium ion concentration
negative regulation of cytosolic calcium ion concentration
regulation of ryanodine-sensitive calcium-release channel activity
regulation of cell communication by electrical coupling involved in cardiac conduction
positive regulation of relaxation of cardiac muscle
regulation of calcium ion transmembrane transport
regulation of heart contraction
calcium ion homeostasis
negative regulation of calcium ion import into sarcoplasmic reticulum
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support