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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HRH1 Fusion Protein Ag4067 (211-426 aa encoded by BC060802) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.33 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: AKIYKAVRQ HCQHRELINR SLPSFSEIKL RPENPKGDAK KPGKESPWEV LKRKPKDAGG GSVLKSPSQT PKEMKSPVVF SQEDDREVDK LYCFPLDIEH MQAAAEGSSR DYVAVNRSHG QLKTDEQGLN THGASEISED QMLGDSQSFS RTDSDTTTET APGKGKLRSG SNTGLDYIKF TWKRLRSHSR QYVSGLHMNR ERKAAKQLGF IMAAFIL (211-426 aa encoded by BC060802 )
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bordetella pertussis induced histamine sensitization; H1 receptor; H1R; HH1R; Histamine H1 receptor; Histamine H1-R; histamine receptor; histamine receptor, subclass H1
Gene Aliases: Bphs; H1-R; H1R; HH1R; Hir; hisH1; Hisr; HRH1
UniProt ID: (Human) P35367, (Mouse) P70174, (Rat) P31390
Entrez Gene ID: (Human) 3269, (Mouse) 15465, (Rat) 24448
Molecular Function:
G-protein coupled receptor
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