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Product Details
PA5-54808
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:1,000-1:2,500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human HRSP12 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.05 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2642545 |
Product Specific Information
Immunogen sequence: GCDFTNVVKT TVLLADINDF NTVNEIYKQY FKSNFPARAA YQVAALPKGS RIEIEAVAIQ GP
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 89%.
Target Information
Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14.5 kDa translational inhibitor protein; 2-iminobutanoate/2-iminopropanoate deaminase; Heat-responsive protein 12; hp14.5; L-PSP; Liver perchloric acid-soluble protein; perchloric acid soluble protein; perchloric acid-soluble protein; perchrolic acid soluble protein; Reactive intermediate imine deaminase A homolog; reactive intermediate/imine deaminase A homolog; ribonuclease UK114; rp14.5; Translation inhibitor L-PSP ribonuclease; translational inhibitor p14.5; translational inhibitor protein p14.5; UK114 antigen homolog
Gene Aliases: HR12; HRP12; HRSP12; P14.5; PSP; PSP1; RIDA; UK114
UniProt ID: (Mouse) P52760, (Rat) P52759, (Human) P52758
Entrez Gene ID: (Mouse) 15473, (Rat) 65151, (Human) 10247
Molecular Function:
deaminase
nuclease activity
endonuclease activity
hydrolase activity
endoribonuclease activity, producing 3'-phosphomonoesters
deaminase activity
long-chain fatty acid binding
phosphoric ester hydrolase activity
protein homodimerization activity
ion binding
T/G mismatch-specific endonuclease activity
poly(A) RNA binding
retroviral 3' processing activity
transition metal ion binding
platinum binding
xenon atom binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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