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Bethyl Laboratories
HS1 Polyclonal Antibody
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FIGURE: 1 / 1
HS1 Antibody (A303-574A) in WB
Detection of human HS1 by western blot and immunoprecipitation. Samples: Whole cell lysate from Jurkat (15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 µg) and HeLa (H; 50 µg) cells. Antibodies: Affinity purified rabbit anti-HS1 antibody (Product # A303-574A) used for WB at 1 µg/mL (A) and 0.4 µg/mL (B) and used for IP at 6 µg/mg lysate. HS1 was also immunoprecipitated by rabbit anti-HS1 antibody A303-573A, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 3 seco... View More
Product Details
A303-574A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 350 and 400 of human Hematopoietic Cell-specific Lyn Substrate 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; LckBP1; p75
Gene Aliases: CTTNL; HCLS1; HS1; lckBP1; p75
UniProt ID: (Human) P14317
Entrez Gene ID: (Human) 3059
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of cell proliferation
response to hormone
positive regulation of phosphatidylinositol 3-kinase signaling
actin filament polymerization
erythrocyte differentiation
regulation of actin filament polymerization
positive regulation of granulocyte differentiation
positive regulation of peptidyl-serine phosphorylation
intracellular signal transduction
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of transcription factor import into nucleus
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of protein kinase B signaling
cellular response to cytokine stimulus
negative regulation of leukocyte apoptotic process
positive regulation of actin cytoskeleton reorganization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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