Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RELAVWPAAA QRKRLLQLPQ WRRRRPPAPR DDGEEAAWEE ES
Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 50%.
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-OST-3A; 30ST3A1; h3-OST-3A; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; heparan sulfate 3-O-sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; heparin-glucosamine 3-O-sulfotransferase
Gene Aliases: 3-OST-3A; 3OST3A1; HS3ST3A; HS3ST3A1; UNQ2551/PRO6180
UniProt ID: (Human) Q9Y663
Entrez Gene ID: (Human) 9955
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