The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
Protein Aliases: 17-beta-HSD 12; 17-beta-hydroxysteroid dehydrogenase 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; Estradiol 17-beta-dehydrogenase 12; hydroxysteroid (17-beta) dehydrogenase 12; KAR; Short chain dehydrogenase/reductase family 12C member 1; short chain dehydrogenase/reductase family 12C, member 1; steroid dehydrogenase homolog; Very-long-chain 3-oxoacyl-CoA reductase
Gene Aliases: HSD17B12; KAR; SDR12C1
UniProt ID: (Human) Q53GQ0
Entrez Gene ID: (Human) 51144