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          • Primary Antibodies ›
          • HSD17B8 Antibodies

          Proteintech

          HSD17B8 Polyclonal Antibody

          View all (14) HSD17B8 antibodies

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          Cite HSD17B8 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (20)
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 20

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          HSD17B8 Antibody (16752-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 16752-1-AP) (HSD17B8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HSD17B8 Antibody in Western Blot (WB)
          HSD17B8 Antibody in Western Blot (WB)
          HSD17B8 Polyclonal Antibody

          Product Details

          16752-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          HSD17B8 Fusion Protein Ag10226 (1-261 aa encoded by BC008185)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Amount

          19.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MASQLQNRL RSALALVTGA GSGIGRAVSV RLAGEGATVA ACDLDRAAAQ ETVRLLGGPG SKEGPPRGNH AAFQADVSEA RAARCLLEQV QACFSRPPSV VVSCAGITQD EFLLHMSEDD WDKVIAVNLK GTFLVTQAAA QALVSNGCRG SIINISSIVG KVGNVGQTNY AASKAGVIGL TQTAARELGR HGIRCNSVLP GFIATPMTQK VPQKVVDKIT EMIPMGHLGD PEDVADVVAF LASEDSGYIT GTSVEVTGGL FM (1-261 aa encoded by BC008185)

          Target Information

          NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; H FABGL; KAR alpha subunit; ke-6; Ke6; Protein Ke6; really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8

          View more View less

          Gene Aliases: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; HSD17B8; KE6; RING2; SDR30C1

          View more View less

          UniProt ID: (Human) Q92506, (Rat) Q6MGB5

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          Entrez Gene ID: (Human) 7923, (Rat) 361802

          View more View less

          Function(s)
          estradiol 17-beta-dehydrogenase activity protein binding oxidoreductase activity testosterone dehydrogenase (NAD+) activity quinone binding NADH binding (3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity 3-hydroxyacyl-CoA dehydrogenase activity oxidoreductase
          Process(es)
          lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process steroid biosynthetic process estrogen biosynthetic process androgen metabolic process estrogen metabolic process protein heterotetramerization oxidation-reduction process
          It has to be done as per old AB suggested Products section.

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