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Product Details
16752-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HSD17B8 Fusion Protein Ag10226 (1-261 aa encoded by BC008185) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.13 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MASQLQNRL RSALALVTGA GSGIGRAVSV RLAGEGATVA ACDLDRAAAQ ETVRLLGGPG SKEGPPRGNH AAFQADVSEA RAARCLLEQV QACFSRPPSV VVSCAGITQD EFLLHMSEDD WDKVIAVNLK GTFLVTQAAA QALVSNGCRG SIINISSIVG KVGNVGQTNY AASKAGVIGL TQTAARELGR HGIRCNSVLP GFIATPMTQK VPQKVVDKIT EMIPMGHLGD PEDVADVVAF LASEDSGYIT GTSVEVTGGL FM (1-261 aa encoded by BC008185)
Target Information
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; H FABGL; hydroxysteroid (17-beta) dehydrogenase 8; KAR alpha subunit; ke-6; Ke6; Protein Ke6; really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; short chain dehydrogenase/reductase family 30C, member 1; Testosterone 17-beta-dehydrogenase 8
Gene Aliases: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; HSD17B8; KE6; RING2; SDR30C1
UniProt ID: (Human) Q92506, (Rat) Q6MGB5
Entrez Gene ID: (Human) 7923, (Rat) 361802
Molecular Function:
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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