This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: GQTNYAASKA GVIGLTQTAA RELGRHGIRC NSVLPGFIAT PMTQKVPQKV VDKITEMIPM GHLGDPEDVA DVVAFLASED SGY
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; H FABGL; hydroxysteroid (17-beta) dehydrogenase 8; KAR alpha subunit; ke-6; Ke6; Protein Ke6; really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; short chain dehydrogenase/reductase family 30C, member 1; Testosterone 17-beta-dehydrogenase 8
Gene Aliases: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; HSD17B8; KE6; RING2; SDR30C1
UniProt ID: (Human) Q92506
Entrez Gene ID: (Human) 7923
Molecular Function: oxidoreductase