Positive Control: NCI-H929
Predicted Reactivity: Rhesus Monkey (96%), Chimpanzee (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor and a costimulatory signal provided primarily by CD28 in naive T cells. HSH2 is a target of both of these signaling pathways.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adaptor in lymphocytes of unknown function X; FLJ14886; Hematopoietic SH2 domain-containing protein; Hematopoietic SH2 protein
Gene Aliases: ALX; HSH2; HSH2D
UniProt ID: (Human) Q96JZ2
Entrez Gene ID: (Human) 84941