This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
PA5-34760 targets HSP60/Heat Shock Protein 60 in ICC, IF, IHC (P), and WB applications and shows reactivity with Human, Mouse, and Rat samples.
The PA5-34760 immunogen is recombinant fragment corresponding to a region within amino acids 205 and 483 of HSP60 (Uniprot ID#P10809).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
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Protein Aliases: 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein, 60 kDa; HLD4; HSP-60; HSP-65; HSP65; HuCHA60; mitochondrial; Mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; SPG13
Gene Aliases: 60kDa; CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HSPD1; Hspd1-30p; HuCHA60; SPG13