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Invitrogen
HSPA14 Polyclonal Antibody
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FIGURE: 1 / 1
HSPA14 Antibody (PA5-96580) in WB
Western blot analysis of HSPA14 in extracts of various cell lines. Samples were incubated with HSPA14 Polyclonal antibody (Product # PA5-96580) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-96580
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_0573832)
Conjugate
Form
Liquid
Concentration
1.26 mg/mL
Amount
126 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ASEFQRSFKH DVRGNARAMM KLTNSAEVAK HSLSTLGSAN CFLDSLYEGQ DFDCNVSRAR FELLCSPLFN KCIEAIRGLL DQNGFTADDI NKVVLCGGSS RIPKLQQLIK DLFPAVELLN SIPPDEVIPI GAAIEAGILI GKENLLVEDS LMIECSARDI LVKGVDESGA SRFTVLFPSG TPLPARRQHT LQAPGSISSV CLELYESDGK NSAKEETKFA QVVLQDLDKK ENGLRDILAV LTMKRDGSLH VTCTDQETGK CEAISIEIAS; Positive Samples: MCF7, SW620, COS-1, HeLa, Jurkat, Mouse spleen, Mouse brain, Mouse thymus; Cellular Location: Cytoplasm, cytosol
Target Information
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14; Heat shock protein; heat shock protein 4; Heat shock protein family A member 14; Heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP70-like protein 1; HSP7E; hsr-1; NST-1; hsr.1; NST-1; unnamed protein product
Gene Aliases: 70kDa; HSP60; HSP70-4; HSP70L1; HSPA14; hsr.1; MSANTD7; NST-1
UniProt ID: (Human) Q0VDF9, (Mouse) Q99M31
Entrez Gene ID: (Human) 51182, (Mouse) 50497
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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