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Invitrogen

HSPA1B Polyclonal Antibody

1 Published Figure
1 Reference
View all (26) HSPA1B antibodies

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HSPA1B Polyclonal Antibody

Product Details

PA5-97846

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

ELISA (ELISA)

Assay-Dependent
-
Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Mouse Heat shock 70 kDa protein 1B protein (2-642AA)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.5 mg/mL

Amount

100 µg

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2812460

Target Information

This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 68 kDa heat shock protein; Heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; heat shock 70kD protein 1B; heat shock 70kDa protein 1B; Heat shock protein; heat shock protein 70.1; Heat shock protein family A member 1A; Heat shock protein family A member 1B; heat shock protein, 70 kDa 1; HSP; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; HSP70.1; HSP70.1/HSP70.2; HSP70I; unnamed protein product

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Gene Aliases: Hcp70.1; hsp68; Hsp70; HSP70-1; HSP70-1B; HSP70-2; HSP70.1; HSP70.2; Hsp70a1; HSP72; HSPA1; HSPA1A; HSPA1B; HSX70

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UniProt ID: (Human) P0DMV8, (Mouse) P17879

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Entrez Gene ID: (Human) 3304, (Mouse) 15511

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Function(s)
nucleotide binding virus receptor activity G-protein coupled receptor binding RNA binding receptor binding protein binding ATP binding ATPase activity enzyme binding heat shock protein binding ubiquitin protein ligase binding histone deacetylase binding protein binding involved in protein folding unfolded protein binding C3HC4-type RING finger domain binding ATP-dependent protein disaggregase activity ATP-dependent protein folding chaperone
Process(es)
binding of sperm to zona pellucida response to heat negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process mRNA catabolic process protein folding negative regulation of cell proliferation positive regulation of gene expression negative regulation of cell growth regulation of protein ubiquitination negative regulation of protein ubiquitination positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of interleukin-8 production cellular response to oxidative stress cellular response to heat protein refolding positive regulation of erythrocyte differentiation ATP metabolic process viral entry into host cell protein stabilization positive regulation of NF-kappaB transcription factor activity cellular heat acclimation positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway cellular response to steroid hormone stimulus positive regulation of microtubule nucleation negative regulation of inclusion body assembly regulation of mitotic spindle assembly positive regulation of tumor necrosis factor-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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