Immunogen sequence: ILNVTAADKS TGKENKITIT NDKGRLSKDD IDRMVQEAER YKSEDEANRD RVAAKNALES YTYNIKQTVE DEKLRGKISE QDKNKILDKC QEVINWLDRN QMAEKDEYEH KQKELERVCN PIISKLYQGG PGGGSGGGGS GASGGPTIEE
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
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Protein Aliases: Heat shock 70 kDa protein 2; heat shock 70kD protein 2; heat shock 70kDa protein 2; Heat shock protein 70.2; heat shock protein alpha 2; heat shock protein, 70 kDa 2; Heat shock-related 70 kDa protein 2; HST; Testis-specific heat shock protein-related; testis-specific heat shock protein-related gene hst70
Gene Aliases: 70kDa; Hcp70.2; HSP70-2; HSP70-3; HSP70.2; HSP70A2; HSPA2; Hspt70; Hst70