Immunogen sequence: FEELGKQIQQ YMKIISSFKN KEDQYDHLDA ADMTKVEKST NEAMEWMNNK LNLQNKQSLT MDPVVKSKEI EAKIKELTST CSPIISKPKP KVEPPKEEQK NAEQNGPVDG
This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 5a; Heat shock 70 kDa protein 4; Heat shock 70-related protein APG-2; heat shock 70kD protein 4; heat shock 70kDa protein 4; heat shock protein, 110 kDa; HS24/P52; hsp70 RY; HSP70RY; HSPH2; Ischemia responsive 94 kDa protein
Gene Aliases: 70kDa; AI317151; APG-2; APG2; HEL-S-5a; HS24/P52; Hsp110; Hsp70; Hsp70RY; HSPA4; HSPH2; Irp94; mKIAA4025; RY