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Product Details
H00023640-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HSPBP1 (NP_036399.3, 1 a.a. approximately 359 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSDEGSRGSR LPLALPPASQ GCSSGGGGGG SSAGGSGNSR PPRNLQGLLQ MAITAGSEEP DPPPEPMSEE RRQWLQEAMS AAFRGQREEV EQMKSCLRVL SQPMPPTAGE AEQAADQQER EGALELLADL CENMDNAADF CQLSGMHLLV GRYLEAGAAG LRWRAAQLIG TCSQNVAAIQ EQVLGLGALR KLLRLLDRDA CDTVRVKALF AISCLVREQE AGLLQFLRLD GFSVLMRAMQ QQVQKLKVKS AFLLQNLLVG HPEHKGTLCS MGMVQQLVAL VRTEHSPFHE HVLGALCSLV TDFPQGVREC REPELGLEEL LRHRCQLLQQ HEEYQEELEF CEKLLQTCFS SPADDSMDR
Target Information
HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Heat shock protein; Heat shock protein-binding protein 1; HSP; hsp70 interacting protein; Hsp70-binding protein 1; Hsp70-binding protein 2; Hsp70-interacting protein 1; Hsp70-interacting protein 2; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HspBP1; HspBP2
Gene Aliases: FES1; HSPBP; HSPBP1; PP1845
UniProt ID: (Human) Q9NZL4
Entrez Gene ID: (Human) 23640
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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