Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Heat shock protein; Heat shock protein-binding protein 1; HSP; Hsp70-binding protein 1; Hsp70-interacting protein 1; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HspBP1
Gene Aliases: Hspbp; Hspbp1
UniProt ID: (Rat) Q6IMX7
Entrez Gene ID: (Rat) 246146
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support