FIGURE: 1 / 14
Immunogen sequence: MSGTNLDGN DEFDEQLRMQ ELYGDGKDGD TQTDAGGEPD SLGQQPTDTP YEWDLDKKAW FPKITEDFIA TYQANYGFSN DGASSSTANV EDVHARTAEE PPQEKAPEPT DARKKGEKRK AESGWFHVEE DRNTNVYVSG LPPDITVDEF IQLMSKFGII MRDPQTEEFK VKLYKDNQGN LKGDGLCCYL KRESVELALK LLDEDEIRGY KLHVEVAKFQ LKGEYDASKK KKKCKDYKKK LSMQQKQLDW RPERRAGPSR MRHERVVIIK NMFHPMDFED DPLVLNEIRE DLRVECSKFG QIRKLLLFDR HPDGVASVSF RDPEEADYCI QTLDGRWFGG RQITAQAWDG T (1-350 aa encoded by BC009896)
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cofactor required for Tat activation of HIV-1 transcription; HIV TAT specific factor 1; HIV Tat-specific factor 1; HIV Tat-specific factor 1 homolog; RP1-196E23.2; Tat-SF1
Gene Aliases: 1600023H17Rik; 2600017A12Rik; 2700077B20Rik; dJ196E23.2; HTATSF1; RGD1563377; TAT-SF1; TATSF1