Invitrogen

HTR1A Polyclonal Antibody

View all (12) HTR1A antibodies

Questions & Answers

Questions & Answers

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HTR1A Antibody in Immunohistochemistry (Frozen) (IHC (F)) — Immunohistochemistry analysis of HTR1A in frozen rat cerebellum. Samples were probed with HTR1A polyclonal antibody (Product # PA5-77745) using a dilution of 1:100, and incubated with Hoechst.

HTR1A Antibody in Western Blot (WB) — Western blot analysis of mouse brain membrane (lanes 1 and 3) and rat brain membrane (lanes 2 and 4) with HTR1A polyclonal antibody (Product # PA5-77745) using a dilution of 1:200.

HTR1A Antibody — KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine Receptor 1A

Product Details

PA5-77745

Applications	Tested Dilution	Publications
Western Blot (WB)	1:200	-
Immunohistochemistry (IHC)	1:200	-

Product Specifications
Species Reactivity	Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine Receptor 1A View antigen
Conjugate	Unconjugated
Form	Lyophilized
Concentration	0.8 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.4, with 1% BSA
Contains	0.05% sodium azide
Storage conditions	-20°C
RRID	AB_2735934

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5-HT-1A; 5-HT1A; 5-HT1A receptor; 5-hydroxytryptamine receptor 1A; G-protein coupled receptor 18; Serotonin receptor 1A

Gene Aliases: 5HT1A; Gpcr18; Htr1a; RAT5HT1A

UniProt ID: (Mouse) Q64264, (Rat) P19327

Entrez Gene ID: (Mouse) 15550, (Rat) 24473

Molecular Function: G-protein coupled receptor

behavioral fear response signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway serotonin receptor signaling pathway behavior cell proliferation regulation of serotonin secretion positive regulation of microtubule depolymerization exploration behavior regulation of dopamine metabolic process vasoconstriction serotonin metabolic process regulation of hormone secretion regulation of behavior regulation of feeding behavior NMDA glutamate receptor clustering

Process(es)

G-protein alpha-subunit binding signal transducer activity G-protein coupled receptor activity G-protein coupled serotonin receptor activity drug binding serotonin binding protein binding