This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%) Bovine, Rabbit, Pig (88%).
HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT 2B receptor; 5-HT-2B; 5-HT-2F; 5-HT2B; 5-HT2b receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B; 5-hydroxytryptamine receptor 2B variant b; 5HT2B Receptor; NP75 protein; Serotonin receptor 2B; Stomach fundus serotonin receptor
Gene Aliases: 5-HT(2B); 5-HT-2B; 5-HT2B; AJ012488; AV377389; HTR2B; Srl
Molecular Function: G-protein coupled receptor