PA1-24285 detects 5-HT3A receptor in human samples.
PA1-24285 has been successfully used in Western blot procedures. Dilute using 5% skim milk/PBS buffer mixture.
The PA1-24285 immunogen is a synthetic peptide corresponding to a region of human HTR3A.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT-3; 5-HT3-A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; Serotonin receptor 3A; Serotonin-gated ion channel receptor
Gene Aliases: 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3; HTR3A
UniProt ID: (Human) P46098
Entrez Gene ID: (Human) 3359