Peptide sequence: PLWACILVAA GILATDTHHP QDSALYHLSK QLLQKYHKEV RPVYNWTKAT
Sequence homology: Cow: 79%; Dog: 77%; Guinea Pig: 79%; Human: 100%; Mouse: 77%; Pig: 86%; Rabbit: 86%; Rat: 79%
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine , a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT-3B; 5-HT3 receptor subunit B; 5-HT3-B; 5-HT3B; 5-hydroxytryptamine (serotonin) receptor 3B; 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic; 5-hydroxytryptamine 3 receptor B subunit; 5-hydroxytryptamine receptor 3B; ionotropic; Serotonin receptor 3B; serotonin-gated ion channel subunit
Gene Aliases: 5-HT3B; HTR3B