Positive Control: mouse brain
Predicted Reactivity: Human (91%), Rat (100%), Pig (87%), Bovine (89%), Guinea pig (90%)
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This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
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Protein Aliases: 5-HT-4; 5-HT4 receptor; 5-hydroxytryptamine receptor 4; 5HT4; 5HT4 receptor; Serotonin receptor 4
Gene Aliases: 5-HT-4; 5-HT4; 5-HT<4L>; 5HTR4; Htr4
UniProt ID: (Mouse) P97288
Entrez Gene ID: (Mouse) 15562
Molecular Function: G-protein coupled receptor